Amsphere A3 Logo RGB 2021NOV23

Amsphere™ A3 is a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing.


JSR Life Sciences Parallax Scrolling Amsphere 2021SEP13-1

Current A3 Programs 


Phase I


Phase II


Phase III



Commercial Programs  1

Catalog Numbers & Product Sizes

  • North America, EMEA & APAC Regions


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Why use Amsphere™ A3?


Why Amsphere A3 is an Outstanding Choice for Antibody Fragment & FC-Fusion Purification

Universal Affinity Resin for
Non-classical mAbs

Simplify Your Supply Chain
& Minimize Costs

Impurity Clearance

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Upcoming Webinar

Resin Replacement Study Using JSR Amsphere A3 and a Platform Resin to Reduce the Supply Risk of Protein A Resin

This webinar will demonstrate a comparison of A3 and MabSelect SuRe LX resin performance in test processing of two different IgG1 targets via affinity chromatography, flow-through anion exchange and capture cation exchange chromatography. The data indicates that A3-based processing offers similarly fine performance of yield (80% total), host cell protein clearance, ligand leaching, and aggregate removal. We will also review mass spectrometry analysis of host cell protein clearance by the various process operations.

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Presenter:Tomoya Norinobu
Global Technical Services
Applications Scientist
JSR Life Sciences

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