Amsphere A+ builds on the robust Amsphere protein A legacy with a re-engineered ligand with 1M NaOH tolerance and better binding capacity, plus a redesigned 60 micron bead for improved pressure-flow properties.
How Can Amsphere™ A+ Help Me?
JSR Life Sciences proudly presents Amsphere A+, an advanced affinity resin for the purification of antibodies and antibody derivatives. Building on the success of Amsphere A3, which has been on the market since 2016 and used in over 150 drug product clinical trials, Amsphere A+ delivers superior performance for next-generation biologics.
Higher Dynamic Binding Capacity (DBC)
- Achieves a higher DBC through controlled ligand conformation and orientation.
- Designed to meet the demands of increasing harvest titers.
1M NaOH Caustic Stability
- Improved stability and ligand linking chemistry, sustaining over 94% DBC after 24 hours in 1M NaOH.
- Enables stronger resin cleaning between cycles, meeting the needs of complex biologics.
Improved Pressure-Flow Dynamics
- Larger 60-micron beads improve pressure flow up to 400 cm/h in column diameters above 30 cm.
Catalog Numbers & Product Sizes
Product Lineup: Resin Slurry
Product Lineup: Pre-packed Columns
Protein A Mix-N-Go™ ELISA for Amsphere™ A+ Ligand
This kit is designed for use specifically in quantitating JSR Life Sciences' Protein A Amsphere™ A+ ligand used in the Amsphere A+ protein A chromatography resin. This Mix-N-Go™ Assay eliminates most product antibody inhibition and provides accurate quantitation through the use of a quick 5-minutes sample treatment step that does not require sample boiling and the subsequent centrifugation step, thereby reducing assay time by more than 1 hour.
