Amsphere A+
A next generation, high capacity Protein A chromatography resin for advanced protein separation in downstream processing.
Offering Modern Bioprocess
Products & Services
Our advanced bioprocess products and services provide the ability to shorten your drug development timelines.
CELLiST™ BASAL CHO MX
A well-balanced combination of amino acids & essential nutrients, ensuring robust cell growth & maximum productivity in biologics manufacturing
KBI Biopharma
KBI Biopharma is an award-winning biopharmaceutical contract services organization providing fully-integrated, accelerated drug development and biomanufacturing services to pharmaceutical and biotechnology companies globally.
Presenter: Hunter Reese Ph.D.
Scientist, KBI Biopharma Inc.
Webinar
Development of effective purification process for bispecifics using affinity capture and mix-mode polishing chromatography
KBI Biopharma and JSR Life Sciences have developed processes for the purification of BsAbs utilizing Amsphere A3 affinity chromatography followed by two polishing steps to eliminate undesirable homodimers and other impurities.
Amsphere A3’s superior binding capacity, resin lifetime, and caustic stability can provide a cost effective, supply-chain stable purification strategy when paired with well-designed polishing steps. In addition to A3 affinity capture, KBI’s platform BsAb purification process includes mixed-mode anion exchange and cation exchange to eliminate homodimeric impurities.
OnDemand Webinar
Effective Cleaning and Sanitization of a Protein A Resin
This webinar will discuss the efficacy of cleaning off proteinaceous fouling from a methacrylate-based Protein A resin for an extensive range of CIP protocols. Furthermore, an in-depth statistical analysis is presented on the cleaning effects of both NaOH concentration and contact time. Together with the impact on DBC retention, this can assist process engineers in developing intensified cleaning strategies. Finally, guidelines are presented for using peracetic acid to sanitize the resin in the event of contamination with spore-forming bacteria.
Please join us to learn more!
Presenter: Gerald Platteau
Senior Application Engineer
JSR Life Sciences