Crown Bioscience

Industry-leading Preclinical Services in Oncology

About Crown Bioscience


Crown Bioscience is a global contract research organization (CRO) dedicated to improving human health through partnering with biotech and pharmaceutical companies that drive drug discovery and development in oncology and immuno-oncology.

We deliver a broad spectrum of integrated solutions, which include preclinical research services, translational platforms, and clinical trial support. We have the world's largest commercially available patient-derived xenograft (PDX) collection and offer tumor organoid services using leading Hubrecht Organoid Technology, with over 600 models across 22 cancer indications.

Our expertise extends across a diverse portfolio of platforms and services, including in vivo, in vitro, ex vivo, and in silico methods, as well as advanced laboratory services that cover the entire drug development timeline. Additionally, we maintain an extensive biobank of liquid and human biospecimens, complete with clinical histories.

Operating from 11 facilities across the US, Europe, and APAC, including laboratories accredited by the College of American Pathologists (CAP) and the International Organization for Standardization (ISO), ensuring the highest standards of quality and reliability in our research environments.

 

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Peer Reviewed Papers

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Largest commercially available PDX collection

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Scientific posters presented annually

Crown Bioscience Offerings

 

Translational Platforms: Utilizing in vitro and in vivo models and technologies such as PDX, CDX, organoids, biospecimens, and CRISPR/Cas9 gene editing to answer crucial questions in cancer biology and assess treatment efficacy. We offer specialized services in biomarkers and bioanalysis discovery leveraging data science and bioinformatics.

Target Solutions: Targeting crucial aspects of oncology research areas such as genetic mutations (KRAS and EGFR), drug resistance, patient tissue analysis, antibody-drug conjugates (ADCs), and progressing immuno-oncology molecules. Our solutions offer valuable insights, supporting the development of targeted therapies and enhancing patient outcomes.

Innovative Technologies: Our core services integrate bioinformatics and biomarker analyses to advance preclinical biomarker discovery. This includes tools like CRISPR/Cas9, genomics, high-content imaging (HCI), and mass spectrometry, along with expertise in ex vivo patient tissue (EVPT) platforms and spatial multi-omics analyses, ensuring data with high precision and reliability.

Advanced Services: Utilizing bioinformatics, genomics, and proteomics analyses, we optimize your research strategies. Including platforms for biomarker discovery, DMPK, efficacy testing, pharmacology and bioanalytical, screening, toxicology, and consulting services.

Professional service with sense of urgency. Very wide of range of models available. Reliable service. Additional technical help is always at hand.
DukeStreetBio
Globally I am extremely satisfied with the data quality provided and fast delivery/time to initiate studies from Crown Bioscience. Reactivity is excellent so far; please keep the tempo.
BoehringerIngelheimRCVGmbHCoKGDr
Efficient, well performed study with excellent experimental execution. We were pleased with the input for the experimental design and outcome. Scientists worked to understand and provide quality experimental results.
Normunity
There are many competitors.  I stick with Crown Bioscience because I trust the data.
KumquatBiosciences
Crown Bioscience is best in the world for the in vivo studies/pharmacology. Keep it up.
SimchaTherapeutics
They [Crown Bioscience] are super easy to work with and do a great job getting quality data from studies at a reasonable price.
NextpointTherapeautics

Customers Love Crown Bioscience

Crown Bioscience boasts the best Customer Experience in the Industry, explore our data below.

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Studies Completed
888

Studies Completed

This data point indicates the total number of studies in Q2 2023 that the CSAT, Customer Effort, and Customer Expectation scores are measured against.

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Customer Satisfaction
96%

Customer Satisfaction

Also known as CSAT, this metric indicates how satisfied customers are with the complete Crown Bioscience customer experience.

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Customer Effort
96%

Customer Effort

The Customer Effort Score (CES) is a metric that measures how easy it was to work with Crown Bioscience.

Customer Satisfaction Report

Latest Crown Bioscience News

The Only licenced Preclinical CRO Service Provider for HUB Tumor Organoids