JSR Life Sciences Background

 

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Hyper-productive mAb Capture

Application Notes: Obtaining 200 g/L/h productivity in a hyper-productive affinity capture of monoclonal antibodies using lattice supported Chromassette and 30 µm Amsphere A3 resin.

JSR’s unique Chromassette™ modular chromatography platform was shown to support the feasibility of capturing 3 kg of monoclonal antibody per hour using 15 liters of a prototype 30 µm diameter JSR Amsphere™ Protein A-based affinity resin.

A tenfold increase in productivity of 200 g/L/h compared to the industry norm was possible through an intensified Protein A capture process.

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