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JSR Appplication Note AN-C4 Single Page Letter 2021MAR04 V07 D-page-001

 

AN-C4 HYPER-PRODUCTIVE Process

Learn More About Chromassette®: Obtaining 200 g/L/h productivity in a hyper-productive affinity capture of monoclonal antibodies using lattice supported Chromassette and 30 µm Amsphere A3 resin.

JSR’s unique Chromassette™ modular chromatography platform was shown to support the feasibility of capturing 3 kg of monoclonal antibody per hour using 15 liters of a prototype 30 µm diameter JSR Amsphere™ Protein A-based affinity resin. A tenfold increase in productivity of 200 g/L/h compared to the industry norm was possible through an intensified Protein A capture process.

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