A next generation, high capacity Protein A chromatography resin for advanced protein separation in downstream processing.
This webinar will discuss the efficacy of cleaning off proteinaceous fouling from a methacrylate-based Protein A resin for an extensive range of CIP protocols. Furthermore, an in-depth statistical analysis is presented on the cleaning effects of both NaOH concentration and contact time. Together with the impact on DBC retention, this can assist process engineers in developing intensified cleaning strategies. Finally, guidelines are presented for using peracetic acid to sanitize the resin in the event of contamination with spore-forming bacteria.
Please join us to learn more!
Presenter: Gerald Platteau
Senior Application Engineer
JSR Life Sciences
KBI Biopharma Inc. has developed a rapid and streamlined workflow for comparing capacity and product quality from different ProA resin candidates as part of the larger downstream purification process development effort. This workflow has been utilized to compare Amsphere A3 resin to other high-performance Protein A resins available on the market since 2016. This presentation will cover the results of these comparisons in terms of ProA resin capacity and eluate product quality as well as later development data comparing viral clearance results for these different affinity resins.