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Introducing Amsphere™ A3 

A next generation Protein A chromatography resin.

Amsphere A3 is a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing.

Besides an outstanding high capacity, Amsphere A3 has an overall improved process robustness, flow characteristics, optimized impurity removal, productivity and resin lifetime.

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Our Products

We offer a variety of life sciences products across all stages of biopharmaceutical development and manufacturing 

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Amsphere A3

A next generation, high capacity protein A chromatography resin for advanced protein separation in downstream processing.

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An innovative chromatography platform that helps improve the operational efficiency & productivity of your purification processes.
Product under development.

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Hydrophilic & hydrophobic magnetic microparticles which can be used for life science research & in vitro diagnostic use.

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Blocking agent composed of 100% chemically synthesized polymers, devoid of the safety & purity issues of biological blocking reagents.

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Uniform-sized polystyrene latex particles for agglutination tests in clinical diagnostics with a variety of sizes & surfaces available.

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MBL provides biomarker discovery for companion and in vitro diagnostics.

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Our Services

Our affiliates provide a wide range of research, diagnostic, & bioprocess services.

crown-logo-on whiteContract Research

Crown Bio is a contract research & translational technology company making precision medicine a reality.

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Cell Line Development

Selexis SA is the global leader in cell line development with best-in-class modular technology & highly specialized solutions.

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Contract Manufacturing

KBI Biopharma is a contract development and manufacturing organization for the 21st Century.

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Webinar: Packing of Protein-A resins in lab-, pilot- and large-scale columns: How to Achieve a “Right First Time" - Part 2

This web-based, interactive tutorial will help scientists, engineers and operators to achieve a “right first time” packing of the Amsphere A3 Protein-A resin for their lab-, pilot- and large-scale columns. In Part 2 of the webinar series, we will review various column sizes and best practices. For the pilot- and large-scale columns, optimal procedures for different packing principles and variety of column types will be discussed. The tutorial will also include detailed column performance evaluation and troubleshooting.

Latest News

KBI Biopharma Completes Eurofins DiscoverX Products Specialized Bioassay Certification Program

Companies will work together on critical componentsthat canaccelerateclient-sponsored validation programs through downstream drug development

FREMONT, Calif. and DURHAM, N.C.October 11, 2021Eurofins DiscoverX Products,LLC(Eurofins DiscoverX),an industryleader in assays for drug...

Crown Bioscience Launches ‘3D Ex Vivo Patient Tissue Platform’ to Improve Response Predictability to Immuno-Oncology Drug Candidates

Platform combining phenotypic high content imaging analysis and three-dimensional models of fresh patient tumors to provide relevant analysis of drug responses that can inform candidate selection and clinical program design

SUNNYVALE, California, October 7, 2021 – Crown Bioscience, a JSR Life...

MBL to Distribute Qkine’s Animal-free Growth Factors and Cytokines

Tokyo, Japan - September 30, 2021 - Medical & Biological Laboratories Co., Ltd. (MBL), a JSR Life Sciences Company, has signed a distributor agreement with Qkine Ltd. for sale of products in Japan. 

In recent years, there has been an increasing need for reagents that meet the high biological raw...

Webinar: Developing an Effective CIP Strategy for your Protein A Step


Extending the lifetime of Protein A resin during the downstream process of manufacturing a biomolecule can have significant positive effects on your process economy. In this webinar, NaOH in combination with ethylene glycol, ethanol, IPA, and thioglycerol are examined. Bacterial challenge, soaking, and life cycle data on Amsphere A3 resin using PAA will be presented.



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Featured Resources

Looking for a CDx Partner in Japan?


MBL in Japan is a one stop shop. MBL is #1 for new IVD medical reimbursement approvals in Japan with an Extensive KOL Network required for approvals.


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