Amsphere A+
A next generation, high capacity protein A chromatography resin for advanced protein separation in downstream processing.
Amsphere A+ is a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing.
Besides an outstanding high capacity, Amsphere A+ has an overall improved process robustness, flow characteristics, optimized impurity removal, productivity and resin lifetime.
BASAL CHO MX growth medium provides a well-balanced combination of amino acids and essential
nutrients, ensuring robust cell growth and maximum productivity in biologics manufacturing.
CELLiST™ serves as a comprehensive solution for all your biologics manufacturing needs.
This video webinar, presented by Beatriz Catalao of JSR Life Sciences, is on the topic of column packing of protein A resins in lab, pilot, and large-scale columns. Beatriz provides a quick introduction to Amsphere A3, a protein A resin, and highlights the column packing preparation requirements to achieve a successfully packed bed.
Beatriz also mentions the high binding capacity, alkali stability, and impurity removal capabilities of Amsphere A3, emphasizing its added value for default batch and next-generation intensified bioprocessing. Additionally, Beatriz mentions the availability of regional application support, on-site packing support, packing training, and experimental support.
Throughout the webinar, various methods and factors for determining slurry concentration and compression factor are explained, along with guidelines for selecting the right column and bed supports. The video also discusses the recommended compression factors for different column diameter ranges and provides flow rate ranges for different column sizes. Finally, it presents guidelines for resin slurry handling and discusses suitable and unsuitable pump options for transferring the slurry.
This is part one of a webinar series and focuses on the column packing process preparations, with a second webinar planned to cover column packing and evaluation.