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Amsphere A3
A next generation, high capacity protein A chromatography resin for advanced protein separation in downstream processing.
Amsphere A3 is a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing.
Besides an outstanding high capacity, Amsphere A3 has an overall improved process robustness, flow characteristics, optimized impurity removal, productivity and resin lifetime.
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A next generation, high capacity protein A chromatography resin for advanced protein separation in downstream processing.
An innovative chromatography platform that helps improve the operational efficiency & productivity of your purification processes.
Product under development.
Hydrophilic & hydrophobic magnetic microparticles which can be used for life science research & in vitro diagnostic use.
Blocking agent composed of 100% chemically synthesized polymers, devoid of the safety & purity issues of biological blocking reagents.
Uniform-sized polystyrene latex particles for agglutination tests in clinical diagnostics with a variety of sizes & surfaces available.
Providing high-quality products & solutions to advance life science research in the drug discovery & development fields.
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Crown Bio is a contract research & translational technology company making precision medicine a reality.
Selexis SA is the global leader in cell line development with best-in-class modular technology & highly specialized solutions.
KBI Biopharma is a contract development and manufacturing organization for the 21st Century.
KBI Biopharma Inc. has developed a rapid and streamlined workflow for comparing capacity and product quality from different ProA resin candidates as part of the larger downstream purification process development effort. This workflow has been utilized to compare Amsphere A3 resin to other high-performance Protein A resins available on the market since 2016. This presentation will cover the results of these comparisons in terms of ProA resin capacity and eluate product quality as well as later development data comparing viral clearance results for these different affinity resins.
ON DEMAND
Extending the lifetime of Protein A resin during the downstream process of manufacturing a biomolecule can have significant positive effects on your process economy. In this webinar, NaOH in combination with ethylene glycol, ethanol, IPA, and thioglycerol are examined. Bacterial challenge, soaking, and life cycle data on Amsphere A3 resin using PAA will be presented.
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