JSR-AMSPHERE-Bottle-2020MAR10-V05-01 (1)


Optimizing removal of host cell derived impurities during Protein A chromatography step

Doi (2) (1)
Presenter: Ryo Doi, PhD 
Senior Applications Engineer
at JSR Life Sciences


Webinar Overview

Host cell derived impurities such as host-cell proteins (HCP) and DNA can affect product quality, safety, and efficacy.

The impact of intermediate wash conditions during the initial capture step of Protein A will be reviewed during this webinar. Conditions such as pH, salt concentration and additives, including chaotropic agents, organic solvents and surfactants, were examined.

We also demonstrate the use of LC-MS analysis for identifying and monitoring HCPs.

Available on demand!

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